Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 7/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347084 | 0.93 | FAAH (0.57) | GHSRFAAHTRPV1CYP3A4CYP2C9 | |
| SCHEMBL6235125 | 0.88 | FAAH (0.56) | GHSRFAAHTRPV1NPC1RAB9A | |
| SCHEMBL19033766 | 0.84 | GHSR (0.41) | GHSRFAAHTRPV1CYP3A4CYP2C9 | |
| SCHEMBL25890301 | 0.83 | FPR2 (0.56) | GHSRFAAHTRPV1PSMB8 | |
| SCHEMBL16512497 | 0.83 | FAAH (0.51) | GHSRFAAHTRPV1PSMB8CYP17A1 | |
| SCHEMBL6268190 | 0.83 | FAAH (0.63) | GHSRFAAHTRPV1 | |
| SCHEMBL25384603 | 0.82 | FAAH (0.62) | GHSRFAAHTRPV1ALDH1A1 | |
| SCHEMBL31075550 | 0.82 | FAAH (0.65) | GHSRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL6239518 | 0.82 | FAAH (0.65) | GHSRFAAHTRPV1 | |
| SCHEMBL16512496 | 0.82 | FAAH (0.53) | GHSRFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688668-B2 | Long chain base sphingosine kinase inhibitors | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2017-06-27 | — | — | US | disclosed |