Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.65 |
| ▸ | FPR2 | P25090 | 11/20 | 0.54 |
| ▸ | GHSR | Q92847 | 1/20 | 0.49 |
| ▸ | FPR3 | P25089 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268190 | 0.99 | FAAH (0.63) | FAAHTRPV1FPR2GHSRFPR3 | |
| SCHEMBL6235125 | 0.94 | FAAH (0.56) | FAAHTRPV1FPR2GHSRFPR3 | |
| SCHEMBL8347084 | 0.89 | FAAH (0.57) | FAAHTRPV1FPR2GHSR | |
| SCHEMBL31075550 | 0.88 | FAAH (0.65) | FAAHTRPV1FPR2GHSR | |
| SCHEMBL16512497 | 0.84 | FAAH (0.51) | FAAHTRPV1FPR2GHSR | |
| SCHEMBL25384603 | 0.83 | FAAH (0.62) | FAAHTRPV1FPR2GHSR | |
| SCHEMBL8334553 | 0.83 | FAAH (0.56) | FAAHTRPV1GHSR | |
| SCHEMBL16512496 | 0.82 | FAAH (0.53) | FAAHTRPV1GHSR | |
| SCHEMBL19033765 | 0.82 | GHSR (0.53) | FAAHTRPV1GHSR | |
| SCHEMBL16499450 | 0.81 | FAAH (0.49) | FAAHTRPV1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539686-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040167131-A1 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade | PFIZER INC. | 2004-08-26 | — | — | US | disclosed |
| WO-2004024679-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167131-A1 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade | TFPI, SERPINC1, F11 | FAAH 1446/4885TRPV1 3930/4885FPR2 1122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.