Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 6/20 | 0.42 |
| ▸ | HRH1 | P35367 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15027795 | 0.96 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1DGKATHRATHRB | |
| SCHEMBL15027866 | 0.96 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1DGKATHRATHRB | |
| SCHEMBL15027234 | 0.95 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1DGKATHRATHRB | |
| SCHEMBL15027287 | 0.94 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1DGKATHRATHRB | |
| SCHEMBL15027947 | 0.94 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1DGKATHRATHRB | |
| SCHEMBL24368823 | 0.94 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1DGKATHRATHRB | |
| SCHEMBL17123991 | 0.94 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1DGKATHRATHRB | |
| SCHEMBL17123907 | 0.94 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1DGKATHRATHRB | |
| SCHEMBL15027416 | 0.94 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1DGKATHRATHRB | |
| SCHEMBL15028017 | 0.94 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1DGKATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11679158-B2 | Biodegradable lipids for the delivery of active agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| US-11246933-B1 | Biodegradable lipids for the delivery of active agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2022-02-15 | — | — | US | disclosed |
| US-9687448-B2 | Nucleic acid lipid particle formulations | ALNYLAM PHARMACEUTICALS, INC. (US) | 2017-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11246933-B1 | Biodegradable lipids for the delivery of active agents | LIPA, APOB, CETP | L3MBTL1 1228/4885ALDH1A1 3151/4885DGKA 352/4885 |
| US-11679158-B2 | Biodegradable lipids for the delivery of active agents | LIPA, APOB, CETP | L3MBTL1 1228/4885ALDH1A1 3151/4885DGKA 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.