SCHEMBL19034801

SCHEMBL19034801

O=C(O)CCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 3/20 0.65
FOLH1 Q04609 6/20 0.62
RIMKLA Q8IXN7 1/20 0.62
NAALAD2 Q9Y3Q0 1/20 0.62
GNPAT O15228 1/20 0.57
EPHX2 P34913 1/20 0.52
PLA2G2C Q5R387 1/20 0.51
GART P22102 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29588170 1.00 NOD1 (0.65) NOD1FOLH1RIMKLANAALAD2GNPAT
SCHEMBL14167625 1.00 NOD1 (0.65) NOD1FOLH1RIMKLANAALAD2GNPAT
SCHEMBL19049826 1.00 NOD1 (0.65) NOD1FOLH1RIMKLANAALAD2GNPAT
SCHEMBL29518246 1.00 NOD1 (0.65) NOD1FOLH1RIMKLANAALAD2GNPAT
SCHEMBL19049828 1.00 NOD1 (0.65) NOD1FOLH1RIMKLANAALAD2GNPAT
SCHEMBL4407799 1.00 NOD1 (0.65) NOD1FOLH1RIMKLANAALAD2GNPAT
SCHEMBL13753507 1.00 NOD1 (0.65) NOD1FOLH1RIMKLANAALAD2GNPAT
SCHEMBL19049830 0.98 NOD1 (0.68) NOD1FOLH1RIMKLANAALAD2GNPAT
SCHEMBL14167660 0.98 NOD1 (0.68) NOD1FOLH1RIMKLANAALAD2GNPAT
SCHEMBL19049823 0.98 NOD1 (0.68) NOD1FOLH1RIMKLANAALAD2GNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3402811-B1 EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS NOVO NORDISK AS (DK) 2022-03-30 EP claimed
CN-117677628-A GHR binding pending peptides and compositions comprising the same 肽梦想株式会社 2024-03-08 CN disclosed
WO-2023012263-A1 SOLID ORAL PEPTIDE FORMULATIONS NOVO NORDISK A/S (DK) 2023-02-09 WO disclosed
US-20230000949-A1 SOLID COMPOSITIONS COMPRISING A PCSK9 INHIBITOR AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID NOVO NORDISK AS (DK) 2023-01-05 US disclosed
US-20220323544-A1 SOLID COMPOSITIONS COMPRISING AN EGF(A) DERIVATIVE AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID NOVO NORDISK A/S (DK) 2022-10-13 US disclosed
US-11358994-B2 Fatty acid modified human epidermal growth factor SAINT LOUIS UNIVERSITY (US) 2022-06-14 US disclosed
EP-3402811-B1 EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS NOVO NORDISK AS (DK) 2022-03-30 EP disclosed
US-20200190157-A1 FATTY ACID MODIFIED HUMAN EPIDERMAL GROWTH FACTOR SAINT LOUIS UNIVERSITY (US) 2020-06-18 US disclosed
US-10259856-B2 Protease stabilized acylated insulin analogues NOVO NORDISK A/S (DK) 2019-04-16 US disclosed
WO-2019023295-A1 FATTY ACID MODIFIED HUMAN EPIDERMAL GROWTH FACTOR SAINT LOUIS UNIVERSITY (US) 2019-01-31 WO disclosed
US-9688737-B2 Protease stabilized acylated insulin analogues NOVO NORDISK A/S (DK) 2017-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000949-A1 SOLID COMPOSITIONS COMPRISING A PCSK9 INHIBITOR AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID PCSK9, EGFR, PCSK6 NOD1 2285/4885FOLH1 802/4885RIMKLA 1286/4885
US-20200190157-A1 FATTY ACID MODIFIED HUMAN EPIDERMAL GROWTH FACTOR FABP2, FGFR2, FGF2 NOD1 4150/4885FOLH1 1264/4885RIMKLA 1660/4885
US-11358994-B2 Fatty acid modified human epidermal growth factor FABP2, EGFR, HGF NOD1 4643/4885FOLH1 581/4885RIMKLA 2533/4885
US-20220323544-A1 SOLID COMPOSITIONS COMPRISING AN EGF(A) DERIVATIVE AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID PCSK9, EGFR, PCSK6 NOD1 2650/4885FOLH1 543/4885RIMKLA 1460/4885
US-10259856-B2 Protease stabilized acylated insulin analogues IAPP, IDE, LIPE NOD1 3835/4885FOLH1 524/4885RIMKLA 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.