Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | MAX | P61244 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19035689 | 0.81 | KIF11 (0.54) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1754979 | 0.79 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL13301012 | 0.79 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11009249 | 0.78 | MAPT (0.67) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL14521754 | 0.78 | MAPT (0.61) | MAPTKMT2AALDH1A1GPR35TACR1 | |
| SCHEMBL10133740 | 0.76 | MAPT (0.62) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11594274 | 0.75 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL20560321 | 0.75 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL260584 | 0.75 | KIF11 (0.59) | MAPTMEN1KMT2AKDM4EMYC | |
| SCHEMBL11306123 | 0.74 | MAPT (0.61) | MAPTALDH1A1GPR35TACR1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9687832-B2 | Bifunctional organic catalysts | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-06-27 | — | — | US | disclosed |