Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325519 | 0.84 | SMN1; SMN2 (0.42) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL19035604 | 0.81 | MAPT (0.51) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL12377331 | 0.79 | CDK1 (0.55) | KIF11EPHX2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9187022 | 0.79 | KIF11 (0.65) | KIF11EPHX2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10819624 | 0.79 | GAA (0.52) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL9453957 | 0.78 | CDK1 (0.68) | KIF11EPHX2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11510708 | 0.78 | MLYCD (0.65) | KIF11EPHX2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19035711 | 0.76 | SMN1; SMN2 (0.55) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL9811870 | 0.76 | CA12 (0.57) | KIF11EPHX2CDK1TRPV1TGM2 | |
| SCHEMBL12412636 | 0.76 | L3MBTL1 (0.62) | KIF11EPHX2MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9687832-B2 | Bifunctional organic catalysts | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-06-27 | — | — | US | disclosed |