SCHEMBL1903733

SCHEMBL1903733

C[C@]12CC[C@@H]3c4ccc(OC(=O)CCC(=O)O)cc4CC[C@H]3[C@@H]1CC[C@@H]2O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.75
ESR1 P03372 6/20 0.75
SMN1; SMN2 Q16637 5/20 0.75
ADORA3 P0DMS8 2/20 0.75
ATM Q13315 2/20 0.75
PGR P06401 2/20 0.75
AR P10275 2/20 0.75
SLC6A3 Q01959 2/20 0.75
CHRM1 P11229 1/20 0.75
TBXA2R P21731 1/20 0.75
ADRA1A P35348 1/20 0.75
OPRM1 P35372 1/20 0.75
KMT2A Q03164 3/20 0.72
NR3C1 P04150 2/20 0.72
SHBG P04278 2/20 0.72
SLC6A4 P31645 2/20 0.72
HTR2B P41595 2/20 0.72
FYN P06241 1/20 0.72
ADRA2C P18825 1/20 0.72
SLC6A2 P23975 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12180361 1.00 LMNA (0.75) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL7633202 0.94 LMNA (0.73) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL9404736 0.91 LMNA (0.77) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL28077837 0.91 ESR1 (0.77) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL4333126 0.91 LMNA (0.75) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL40564 0.91 LMNA (0.75) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL11102416 0.91 LMNA (0.75) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL547293 0.89 LMNA (0.80) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL2313094 0.89 LMNA (0.73) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL24102647 0.89 LMNA (0.81) LMNAESR1SMN1; SMN2ADORA3ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2062569-B1 Vaginal delivery system BAYER OY (FI) 2011-05-11 EP claimed
WO-2010133757-A1 VAGINAL DELIVERY SYSTEM BAYER SCHERING PHARMA OY (FI) 2010-11-25 WO claimed
US-20100285097-A1 VAGINAL DELIVERY SYSTEM BAYER OY (FI) 2010-11-11 US claimed
CN-101873850-A Vaginal delivery system BAYER SCHERING PHARMA OY 2010-10-27 CN claimed
EP-2227220-A1 VAGINAL DELIVERY SYSTEM Bayer Schering Pharma Oy (FI) 2010-09-15 EP claimed
US-20090142313-A1 VAGINAL DELIVERY SYSTEM BAYER SCHERING PHARMA OY (FI) 2009-06-04 US claimed
WO-2009066006-A1 VAGINAL DELIVERY SYSTEM BAYER SCHERING PHARMA OY (FI) 2009-05-28 WO claimed
EP-2062568-A1 Vaginal delivery system Bayer Schering Pharma Oy (FI) 2009-05-27 EP claimed
EP-2062569-A1 Vaginal delivery system Bayer Schering Pharma Oy (FI) 2009-05-27 EP claimed
US-20080279915-A1 Matrix-Controlled Transdermal Therapeutic System Based on an Adhesive for Administering Norelgestromin or the Combination Thereof with an Estrogen HEXAL AG (DE) 2008-11-13 US claimed
US-20210361920-A1 Drug Delivery Device and System with Metered Dosing for Semi-Solid Compositions Compounding Innovations LLC (US) 2021-11-25 US disclosed
US-20160008376-A1 Compositions, Methods and Uses for Treating Gender-Biased Immune Disorders BIOCOPEA LIMITED (GB) 2016-01-14 US disclosed
WO-2016005599-A1 COMPOSITIONS, METHODS AND USES FOR TREATING GENDER-BIASED IMMUNE DISORDERS BIOCOPEA LIMITED (GB) 2016-01-14 WO disclosed
EP-2062569-B1 Vaginal delivery system BAYER OY (FI) 2011-05-11 EP disclosed
WO-2010133757-A1 VAGINAL DELIVERY SYSTEM BAYER SCHERING PHARMA OY (FI) 2010-11-25 WO disclosed
US-20090142313-A1 VAGINAL DELIVERY SYSTEM BAYER SCHERING PHARMA OY (FI) 2009-06-04 US disclosed
WO-2009066006-A1 VAGINAL DELIVERY SYSTEM BAYER SCHERING PHARMA OY (FI) 2009-05-28 WO disclosed
EP-2062568-A1 Vaginal delivery system Bayer Schering Pharma Oy (FI) 2009-05-27 EP disclosed
EP-2062569-A1 Vaginal delivery system Bayer Schering Pharma Oy (FI) 2009-05-27 EP disclosed
US-20080279915-A1 Matrix-Controlled Transdermal Therapeutic System Based on an Adhesive for Administering Norelgestromin or the Combination Thereof with an Estrogen HEXAL AG (DE) 2008-11-13 US disclosed