SCHEMBL19040773

SCHEMBL19040773

CCCCCCCCCN(CCCCCCCCC)CCC1CCNC1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GNAO1 P09471 9/20 0.42
GNAI3 P08754 8/20 0.41
GNAI1 P63096 8/20 0.41
BCHE P06276 7/20 0.36
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
ADH4 P08319 1/20 0.34
SLC6A1 P30531 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRB2 P47870 1/20 0.33
SLC6A12 P48065 1/20 0.33
SLC6A11 P48066 1/20 0.33
SLC6A13 Q9NSD5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19040837 0.90 BCHE (0.40) GNAO1BCHE
SCHEMBL19032594 0.90 GNAO1 (0.51) GNAO1GNAI3GNAI1BCHE
SCHEMBL19032710 0.88 GNAO1 (0.50) GNAO1GNAI3GNAI1BCHE
SCHEMBL19032614 0.85 GNAO1 (0.43) GNAO1GNAI3GNAI1ADH1CADH1A
SCHEMBL20589493 0.84 GNAI3 (0.42) GNAO1GNAI3GNAI1
SCHEMBL19032412 0.83 DNM1 (0.43) GNAO1GNAI3GNAI1
SCHEMBL19040843 0.83 GNAO1 (0.51) GNAO1GNAI3GNAI1BCHEADH1C
SCHEMBL20684333 0.83 GNAO1 (0.46) GNAO1GNAI3GNAI1BCHE
SCHEMBL23576150 0.83 DNM1 (0.45) GNAO1GNAI3GNAI1
SCHEMBL20589495 0.83 DNM1 (0.45) GNAO1GNAI3GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3638678-B1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS MODERNATX INC (US) 2025-12-03 EP disclosed
EP-4036079-B1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS MODERNATX INC (US) 2025-11-19 EP disclosed
US-12396961-B2 Compounds and compositions for intracellular delivery of agents MODERNATX, INC. (US) 2025-08-26 US disclosed
EP-3394030-B2 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS MODERNATX INC (US) 2025-02-12 EP disclosed
US-12077501-B2 Compounds and compositions for intracellular delivery of agents MODERNATX, INC. (US) 2024-09-03 US disclosed
EP-4036079-A2 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS ModernaTX, Inc. (US) 2022-08-03 EP disclosed
EP-3394030-B1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS MODERNATX INC (US) 2021-12-22 EP disclosed
EP-3394030-B1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS MODERNATX INC (US) 2021-12-22 EP disclosed
US-20210198200-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS ARES CAPITAL CORPORATION, AS AGENT 2021-07-01 US disclosed
US-20210198200-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS ARES CAPITAL CORPORATION, AS AGENT 2021-07-01 US disclosed
US-20210161829-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS ARES CAPITAL CORPORATION, AS AGENT 2021-06-03 US disclosed
US-20210161829-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS ARES CAPITAL CORPORATION, AS AGENT 2021-06-03 US disclosed
US-10799463-B2 Compounds and compositions for intracellular delivery of agents MODERNATX, INC. (US) 2020-10-13 US disclosed
US-10799463-B2 Compounds and compositions for intracellular delivery of agents MODERNATX, INC. (US) 2020-10-13 US disclosed
US-10195156-B2 Compounds and compositions for intracellular delivery of agents MODERNATX, INC. (US) 2019-02-05 US disclosed
US-10195156-B2 Compounds and compositions for intracellular delivery of agents MODERNATX, INC. (US) 2019-02-05 US disclosed
US-20180369419-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS Moderna TX, Inc. (US) 2018-12-27 US disclosed
US-20180333366-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS ARES CAPITAL CORPORATION, AS AGENT 2018-11-22 US disclosed
WO-2017112865-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS MODERNATX, INC. (US) 2017-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10195156-B2 Compounds and compositions for intracellular delivery of agents LNPK, PLTP, PHOSPHO1 GNAO1 3550/4885GNAI3 1599/4885GNAI1 1739/4885
US-20210198200-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS LNPK, PLTP, PHOSPHO1 GNAO1 3550/4885GNAI3 1599/4885GNAI1 1739/4885
US-12396961-B2 Compounds and compositions for intracellular delivery of agents LNPK, PLTP, PHOSPHO1 GNAO1 3550/4885GNAI3 1599/4885GNAI1 1739/4885
US-20180369419-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS LNPK, PLTP, PHOSPHO1 GNAO1 3550/4885GNAI3 1599/4885GNAI1 1739/4885
US-20210161829-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS LNPK, PLTP, PHOSPHO1 GNAO1 3550/4885GNAI3 1599/4885GNAI1 1739/4885
US-20180333366-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS LNPK, PLTP, PHOSPHO1 GNAO1 3550/4885GNAI3 1599/4885GNAI1 1739/4885
US-12077501-B2 Compounds and compositions for intracellular delivery of agents LNPK, PLTP, PHOSPHO1 GNAO1 3550/4885GNAI3 1599/4885GNAI1 1739/4885
US-10799463-B2 Compounds and compositions for intracellular delivery of agents LNPK, PLTP, PHOSPHO1 GNAO1 3550/4885GNAI3 1599/4885GNAI1 1739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.