Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23533397 | 0.88 | ALDH1A1 (0.46) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL19032664 | 0.80 | CYP4F2 (0.43) | ALDH1A1POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL19032782 | 0.78 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1TSHRNAAAPPARG | |
| SCHEMBL19040906 | 0.76 | ALDH1A1 (0.51) | ALDH1A1THRBMAPTTSHRPPARG | |
| SCHEMBL19032508 | 0.75 | MAPT (0.44) | ALDH1A1POLBL3MBTL1KMT2AMAPT | |
| SCHEMBL1195986 | 0.73 | ALDH1A1 (0.52) | ALDH1A1POLBL3MBTL1HTTPPM1B | |
| SCHEMBL1245690 | 0.73 | ALDH1A1 (0.52) | ALDH1A1POLBL3MBTL1HTTPPM1B | |
| SCHEMBL15478676 | 0.72 | DGKA (0.59) | ALDH1A1MAPTTSHRNAAADGKA | |
| SCHEMBL23533328 | 0.71 | FAAH (0.42) | CES2ALDH1A1POLBL3MBTL1MEN1 | |
| SCHEMBL1196123 | 0.71 | ALDH1A1 (0.50) | ALDH1A1POLBL3MBTL1HTTPPM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017112865-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2017-06-29 | — | — | WO | disclosed |