Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19040816 | 1.00 | LTA4H (0.43) | LTA4HTSHRALDH1A1RECQLHPGD | |
| SCHEMBL20667097 | 1.00 | LTA4H (0.43) | LTA4HTSHRALDH1A1RECQLHPGD | |
| SCHEMBL15715715 | 0.98 | LTA4H (0.44) | LTA4HTSHRALDH1A1RECQLHPGD | |
| SCHEMBL15128610 | 0.93 | TSHR (0.45) | LTA4HTSHRALDH1A1RECQLHPGD | |
| SCHEMBL19736626 | 0.89 | TSHR (0.45) | LTA4HTSHRALDH1A1RECQLHPGD | |
| SCHEMBL1703685 | 0.87 | MEN1 (0.42) | MEN1KMT2ATP53 | |
| SCHEMBL4650965 | 0.87 | MEN1 (0.42) | MEN1KMT2ATP53 | |
| SCHEMBL427955 | 0.87 | MEN1 (0.42) | MEN1KMT2ATP53 | |
| SCHEMBL868174 | 0.87 | MEN1 (0.42) | MEN1KMT2ATP53 | |
| SCHEMBL837479 | 0.87 | MEN1 (0.42) | MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017112865-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2017-06-29 | — | — | WO | disclosed |