Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29785786 | 0.82 | LMNA (0.59) | UGT2B7MEN1KMT2AATMMMP9 | |
| SCHEMBL198264 | 0.82 | LMNA (0.59) | UGT2B7MEN1KMT2AATMMMP9 | |
| SCHEMBL2683267 | 0.82 | LMNA (0.59) | UGT2B7MEN1KMT2AATMMMP9 | |
| SCHEMBL4946211 | 0.82 | LMNA (0.59) | UGT2B7MEN1KMT2AATMMMP9 | |
| SCHEMBL30367064 | 0.81 | UGT2B7 (0.60) | UGT2B7MEN1KMT2AATMAOC3 | |
| SCHEMBL15695558 | 0.81 | UGT2B7 (0.60) | UGT2B7MMP9CYP1A2TSHR | |
| SCHEMBL1579310 | 0.80 | UGT2B7 (0.55) | UGT2B7MEN1KMT2AATMMMP9 | |
| SCHEMBL29941132 | 0.80 | UGT2B7 (0.55) | UGT2B7MEN1KMT2AATMMMP9 | |
| Acetic Acid SCHEMBL7514323 | 0.79 | UGT2B7 (0.81) | UGT2B7MEN1KMT2AATMMMP9 | |
| SCHEMBL28555283 | 0.78 | CES2 (0.63) | UGT2B7MEN1KMT2AATMMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10238631-B2 | Sesquiterpene derivatives and their use in inflammation or cancer treatment | ACADEMIA SINICA (TW) | 2019-03-26 | — | — | US | disclosed |
| US-20170182001-A1 | NOVEL SESQUITERPENE DERIVATIVES AND THEIR USE IN INFLAMMATION OR CANCER TREATMENT | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2017-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170182001-A1 | NOVEL SESQUITERPENE DERIVATIVES AND THEIR USE IN INFLAMMATION OR CANCER TREATMENT | GSTK1, MIF, GSTA1 | UGT2B7 1576/4885MEN1 3940/4885KMT2A 3539/4885 |
| US-10238631-B2 | Sesquiterpene derivatives and their use in inflammation or cancer treatment | GSTK1, GSTA1, GTPBP10 | UGT2B7 1727/4885MEN1 3694/4885KMT2A 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.