Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15987294 | 0.95 | C5AR1 (0.47) | C5AR1ENPP2SIGMAR1TRPM8ALDH1A1 | |
| SCHEMBL6374605 | 0.86 | OPRK1 (0.43) | C5AR1ENPP2SIGMAR1TRPM8ALDH1A1 | |
| SCHEMBL30942979 | 0.85 | C5AR1 (0.39) | C5AR1ENPP2SIGMAR1TRPM8ALDH1A1 | |
| SCHEMBL9998686 | 0.83 | CCR5 (0.50) | C5AR1CCR5 | |
| SCHEMBL803680 | 0.83 | C5AR1 (0.56) | C5AR1ALDH1A1CYP2C9CYP2C19PTGDR2 | |
| SCHEMBL6356355 | 0.83 | SIGMAR1 (0.49) | C5AR1ENPP2SIGMAR1ALDH1A1CYP2C9 | |
| SCHEMBL9998607 | 0.79 | CCR5 (0.49) | C5AR1CCR5 | |
| SCHEMBL21872794 | 0.79 | ENPP2 (0.60) | ENPP2SIGMAR1TRPM8ALDH1A1CHRM2 | |
| SCHEMBL15987361 | 0.76 | CYP2C19 (0.49) | ENPP2SIGMAR1TRPM8ALDH1A1CHRM2 | |
| SCHEMBL31601727 | 0.75 | HTR2C (0.51) | ENPP2SIGMAR1TRPM8ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2772484-B1 | BICYCLIC HETEROCYCLIC COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-06-28 | — | — | EP | disclosed |