Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197331 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 | |
| SCHEMBL10021922 | 0.76 | ALDH1A1 (0.70) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 | |
| SCHEMBL14865008 | 0.76 | ALDH1A1 (0.70) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 | |
| SCHEMBL3412115 | 0.76 | ALDH1A1 (1.00) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 | |
| SCHEMBL3416817 | 0.75 | ALDH1A1 (0.68) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 | |
| SCHEMBL557758 | 0.75 | ALDH1A1 (0.68) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 | |
| SCHEMBL13433476 | 0.73 | ALDH1A1 (0.66) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 | |
| SCHEMBL22575889 | 0.73 | ALDH1A1 (0.66) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 | |
| SCHEMBL2445178 | 0.73 | ALDH1A1 (0.59) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 | |
| SCHEMBL20520533 | 0.72 | ALDH1A1 (0.63) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11575156-B2 | Diselenoester electrolyte additives for fast charging lithium ion batteries | StoreDot Ltd. (IL) | 2023-02-07 | — | — | US | disclosed |
| US-11205796-B2 | Electrolyte additives in lithium-ion batteries | StoreDot Ltd. (IL) | 2021-12-21 | — | — | US | disclosed |
| US-20210242497-A1 | DISELENOESTER ELECTROLYTE ADDITIVES FOR FAST CHARGING LITHIUM ION BATTERIES | StoreDot Ltd. (IL) | 2021-08-05 | — | — | US | disclosed |
| US-20210242500-A1 | ELECTROLYTES FOR FAST CHARGING LITHIUM ION BATTERIES HAVING FOUR-CARBON CHAIN ESTERS AS LINEAR COMPONENTS | StoreDot Ltd. (IL) | 2021-08-05 | — | — | US | disclosed |
| US-20210234197-A1 | ELECTROLYTE ADDITIVES FOR FAST CHARGING LITHIUM ION BATTERIES | StoreDot Ltd. (IL) | 2021-07-29 | — | — | US | disclosed |
| US-20190356013-A1 | ELECTROLYTE ADDITIVES IN LITHIUM-ION BATTERIES | StoreDot Ltd. (IL) | 2019-11-21 | — | — | US | disclosed |
| US-20190198912-A1 | ELECTROLYTE ADDITIVES IN LITHIUM-ION BATTERIES | StoreDot Ltd. (IL) | 2019-06-27 | — | — | US | disclosed |
| US-7981919-B2 | Tricyclic heteroaryl piperazines, pyrrolidines and azetidines as serotonin receptor modulators | ATHERSYS, INC. (US) | 2011-07-19 | — | — | US | disclosed |
| US-7981919-B2 | Tricyclic heteroaryl piperazines, pyrrolidines and azetidines as serotonin receptor modulators | ATHERSYS, INC. (US) | 2011-07-19 | — | — | US | disclosed |
| EP-1796663-B1 | TRICYCLIC HETEROARYL PIPERAZINES, PYRROLIDINES AND AZETIDINES AS SEROTONIN RECEPTOR MODULATORS | ATHERSYS INC (US) | 2011-05-04 | — | — | EP | disclosed |
| EP-1796663-A4 | TRICYCLIC HETEROARYL PIPERAZINES, PYRROLIDINES AND AZETIDINES AS SEROTONIN RECEPTOR MODULATORS | ATHERSYS INC (US) | 2009-08-05 | — | — | EP | disclosed |
| US-20090069365-A1 | Tricyclic heteroaryl piperazines, pyrrolidines and azetidines as serotonin receptor modulators | BENNANI YOUSSEF L | 2009-03-12 | — | — | US | disclosed |
| US-20090069365-A1 | Tricyclic heteroaryl piperazines, pyrrolidines and azetidines as serotonin receptor modulators | BENNANI YOUSSEF L | 2009-03-12 | — | — | US | disclosed |
| US-7423056-B2 | Tricyclic heteroaryl piperazines, pyrrolidines and azetidines as serotonin receptor modulators | ATHERSYS, INC. (US) | 2008-09-09 | — | — | US | disclosed |
| US-7423056-B2 | Tricyclic heteroaryl piperazines, pyrrolidines and azetidines as serotonin receptor modulators | ATHERSYS, INC. (US) | 2008-09-09 | — | — | US | disclosed |
| EP-1796663-A2 | TRICYCLIC HETEROARYL PIPERAZINES, PYRROLIDINES AND AZETIDINES AS SEROTONIN RECEPTOR MODULATORS | Athersys, Inc. (US) | 2007-06-20 | — | — | EP | disclosed |
| US-20060079567-A1 | Tricyclic heteroaryl piperazines, pyrrolidines and azetidines as serotonin receptor modulators | ATHERSYS, INC. | 2006-04-13 | — | — | US | disclosed |
| WO-2006028961-A2 | TRICYCLIC HETEROARYL PIPERAZINES, PYRROLIDINES AND AZETIDINES AS SEROTONIN RECEPTOR MODULATORS | ATHERSYS, INC. (US) | 2006-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079567-A1 | Tricyclic heteroaryl piperazines, pyrrolidines and azetidines as serotonin receptor modulators | HTR5A, HTR2C, HTR2A | ALDH1A1 1083/4885CYP2D6 589/4885HDAC3 196/4885 |
| US-20090069365-A1 | Tricyclic heteroaryl piperazines, pyrrolidines and azetidines as serotonin receptor modulators | HTR5A, HTR2C, HTR2A | ALDH1A1 1083/4885CYP2D6 589/4885HDAC3 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.