SCHEMBL22575889

SCHEMBL22575889

CCOC(=S)SCC(=O)[O-].[Na+]

nearest known ligand 0.66

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 known ✓ O43570 1/20 0.33
CA1 known ✓ P00915 1/20 0.33
CA2 known ✓ P00918 1/20 0.33
ALDH1A1 P00352 7/20 0.66
CYP2D6 P10635 1/20 0.66
HDAC3 O15379 3/20 0.47
HDAC1 Q13547 3/20 0.47
HDAC2 Q92769 3/20 0.47
HDAC8 Q9BY41 3/20 0.47
HDAC4 P56524 2/20 0.47
HDAC7 Q8WUI4 2/20 0.47
HDAC10 Q969S8 2/20 0.47
HDAC11 Q96DB2 2/20 0.47
HDAC6 Q9UBN7 2/20 0.47
HDAC9 Q9UKV0 2/20 0.47
HDAC5 Q9UQL6 2/20 0.47
MAPT P10636 6/20 0.43
KMT2A Q03164 5/20 0.42
PKM P14618 2/20 0.42
GAA P10253 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14865008 0.79 ALDH1A1 (0.70) ALDH1A1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL10021922 0.79 ALDH1A1 (0.70) ALDH1A1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL3412115 0.79 ALDH1A1 (1.00) ALDH1A1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL3416817 0.78 ALDH1A1 (0.68) ALDH1A1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL557758 0.78 ALDH1A1 (0.68) ALDH1A1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL13433476 0.76 ALDH1A1 (0.66) ALDH1A1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL20520533 0.74 ALDH1A1 (0.63) ALDH1A1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL557513 0.73 ALDH1A1 (0.61) ALDH1A1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL1904872 0.73 ALDH1A1 (0.61) ALDH1A1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL578887 0.73 ALDH1A1 (0.72) ALDH1A1CYP2D6HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12064730-B2 Polymeric substrates with attached polymeric chains SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-08-20 US disclosed
EP-3728425-B1 POLYMERIC SUBSTRATES WITH ATTACHED POLYMERIC CHAINS 3M INNOVATIVE PROPERTIES CO (US) 2021-12-08 EP disclosed
US-20200368694-A1 POLYMERIC SUBSTRATES WITH ATTACHED POLYMERIC CHAINS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2020-11-26 US disclosed
EP-3728425-A1 POLYMERIC SUBSTRATES WITH ATTACHED POLYMERIC CHAINS 3M Innovative Properties Company (US) 2020-10-28 EP disclosed