Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | STK17B | O94768 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17115222 | 1.00 | CYP1A2 (0.44) | CYP1A2CYP2D6STK17BMAOBMAOA | |
| SCHEMBL17115226 | 1.00 | CYP1A2 (0.44) | CYP1A2CYP2D6STK17BMAOBMAOA | |
| SCHEMBL19051925 | 0.83 | MAOA (0.36) | CYP1A2CYP2D6STK17BMAOBMAOA | |
| SCHEMBL19024329 | 0.83 | MAOA (0.36) | CYP1A2CYP2D6STK17BMAOBMAOA | |
| SCHEMBL302174 | 0.80 | MAPK1 (0.52) | CYP1A2CYP2D6STK17BMAOBMAOA | |
| SCHEMBL29406907 | 0.80 | MAPK1 (0.52) | CYP1A2CYP2D6STK17BMAOBMAOA | |
| SCHEMBL11544354 | 0.76 | MAOA (0.39) | CYP1A2STK17BMAOBMAOAKDM4E | |
| SCHEMBL1365275 | 0.74 | CYP1A2 (0.43) | CYP1A2CYP2D6STK17BMAOBMAOA | |
| SCHEMBL14380259 | 0.73 | MAOA (0.65) | CYP1A2CYP2D6MAOBMAOAKDM4E | |
| SCHEMBL28512593 | 0.73 | MAOA (0.65) | CYP1A2CYP2D6MAOBMAOAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170183356-A1 | New Imaging Agents and Methods of Identifying Same | THR TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183356-A1 | New Imaging Agents and Methods of Identifying Same | DDX3X, DDX21, DAXX | CYP1A2 4117/4885CYP2D6 4490/4885STK17B 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.