Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903923 | 1.00 | TACR1 (0.41) | TACR1LMNADPP4L3MBTL1KMT2A | |
| SCHEMBL1902611 | 0.91 | TACR1 (0.41) | TACR1DPP4KMT2AMEN1 | |
| SCHEMBL1904935 | 0.91 | TACR1 (0.41) | TACR1DPP4KMT2AMEN1 | |
| SCHEMBL1905233 | 0.89 | NTMT1 (0.44) | TACR1DPP4 | |
| SCHEMBL1906955 | 0.89 | NTMT1 (0.44) | TACR1DPP4 | |
| SCHEMBL1902249 | 0.87 | MEN1 (0.39) | TACR1LMNADPP4KMT2AMEN1 | |
| SCHEMBL1904624 | 0.87 | MEN1 (0.39) | TACR1LMNADPP4KMT2AMEN1 | |
| SCHEMBL1905042 | 0.87 | MEN1 (0.39) | TACR1LMNADPP4KMT2AMEN1 | |
| SCHEMBL1907660 | 0.87 | MEN1 (0.47) | TACR1KMT2AMEN1POLB | |
| SCHEMBL1903784 | 0.87 | MEN1 (0.47) | TACR1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051673-A1 | AMINOTHIAZOLE DERIVATIVES USEFUL AS KLK1 INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |