Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2284104 | 0.87 | KDM4E (0.57) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL29447076 | 0.79 | NOS1 (0.61) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL244237 | 0.79 | NOS1 (0.61) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL6230934 | 0.77 | NOS1 (0.62) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL5509147 | 0.77 | SIGMAR1 (0.40) | KDM4EALDH1A1HPGDMAOADYRK1A | |
| SCHEMBL2161251 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL29619913 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL482578 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| Coixol SCHEMBL29389732 | 0.76 | NOS1 (0.61) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| Coixol SCHEMBL912220 | 0.76 | NOS1 (0.61) | KDM4EALDH1A1HPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501695-A2 | 1,4-BENZODIAZEPINE-2,5-DIONES AND RELATED COMPOUNDS WITH THERAPEUTIC PROPERTIES | The Regents Of The University Of Michigan (US) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011062766-A2 | 1,4-BENZODIAZEPINE-2,5-DIONES AND RELATED COMPOUNDS WITH THERAPEUTIC PROPERTIES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-05-26 | — | — | WO | disclosed |
| US-7410752-B2 | Method of producing organic silver salt dispersion, and photothermographic material | FUJIFILM CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |
| US-7332267-B2 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2008-02-19 | — | — | US | disclosed |
| US-20070020566-A1 | Photothermographic material and image forming method | FUJI PHOTO FILM., LTD. | 2007-01-25 | — | — | US | disclosed |
| US-20070015095-A1 | Photothermographic material | FUJI PHOTO FILM CO., LTD. | 2007-01-18 | — | — | US | disclosed |
| EP-1401443-A4 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORP (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1401443-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002098424-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-12-12 | — | — | WO | disclosed |