SCHEMBL19054884

SCHEMBL19054884

COC(=O)CC(c1ccccc1)n1ccnc1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.56
▸ RAB9A P51151 1/20 0.56
▸ CYP24A1 Q07973 13/20 0.54
▸ CYP17A1 P05093 3/20 0.52
▸ KDM4E B2RXH2 1/20 0.51
▸ CYP27B1 O15528 2/20 0.51
▸ CYP26A1 O43174 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7122603 0.87 CYP17A1 (0.53) CYP24A1CYP17A1KDM4ECYP27B1
SCHEMBL19054885 0.87 CYP19A1 (0.58) MAPTRAB9ACYP24A1CYP17A1CYP26A1
SCHEMBL410598 0.85 CYP17A1 (0.56) CYP24A1CYP17A1KDM4ECYP27B1
SCHEMBL6983161 0.84 CYP24A1 (0.56) CYP24A1CYP17A1KDM4ECYP27B1
SCHEMBL20390014 0.83 CYP17A1 (0.51) MAPTRAB9ACYP24A1CYP17A1CYP26A1
SCHEMBL21181022 0.82 CYP17A1 (0.47) MAPTRAB9ACYP24A1CYP17A1CYP26A1
SCHEMBL20390008 0.81 MAPT (0.47) MAPTRAB9ACYP24A1CYP17A1CYP26A1
SCHEMBL19054890 0.79 CYP17A1 (0.56) MAPTCYP24A1CYP17A1CYP27B1
SCHEMBL21976264 0.77 CYP26A1 (0.60) CYP24A1CYP17A1KDM4ECYP26A1
SCHEMBL20830319 0.77 CYP19A1 (0.59) MAPTRAB9ACYP24A1CYP17A1CYP26A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10696845-B2 Energy-sensitive resin composition TOKYO OHKA KOGYO CO., LTD. (JP) 2020-06-30 — — US disclosed
US-10570269-B2 Composition containing microparticles TOKYO OHKA KOGYO CO., LTD. (JP) 2020-02-25 — — US disclosed
US-20190225804-A1 ENERGY-SENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2019-07-25 — — US disclosed
US-10336708-B2 Imidazole compound, metal surface treatment liquid, metal surface treatment method, and laminate production method TOKYO OHKA KOGYO CO., LTD. (JP) 2019-07-02 — — US disclosed
US-20180194930-A1 COMPOSITION CONTAINING MICROPARTICLES TOKYO OHKA KOGYO CO., LTD. (JP) 2018-07-12 — — US disclosed
US-20180194930-A1 COMPOSITION CONTAINING MICROPARTICLES TOKYO OHKA KOGYO CO., LTD. (JP) 2018-07-12 — — US disclosed
US-20170247334-A1 IMIDAZOLE COMPOUND, METAL SURFACE TREATMENT LIQUID, METAL SURFACE TREATMENT METHOD, AND LAMINATE PRODUCTION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2017-08-31 — — US disclosed
US-20170247334-A1 IMIDAZOLE COMPOUND, METAL SURFACE TREATMENT LIQUID, METAL SURFACE TREATMENT METHOD, AND LAMINATE PRODUCTION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2017-08-31 — — US disclosed
EP-3184511-A1 IMIDAZOLE COMPOUND, METAL SURFACE TREATMENT LIQUID, METAL SURFACE TREATMENT METHOD, AND LAMINATE PRODUCTION METHOD Tokyo Ohka Kogyo Co., Ltd. (JP) 2017-06-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10336708-B2 Imidazole compound, metal surface treatment liquid, metal surface treatment method, and laminate production method FASN, SLC27A1, SLC27A2 MAPT 510/4885RAB9A 3276/4885CYP24A1 1784/4885
US-20180194930-A1 COMPOSITION CONTAINING MICROPARTICLES CHMP4B, EXOSC10, EXOSC9 MAPT 35/4885RAB9A 2989/4885CYP24A1 3200/4885
US-20170247334-A1 IMIDAZOLE COMPOUND, METAL SURFACE TREATMENT LIQUID, METAL SURFACE TREATMENT METHOD, AND LAMINATE PRODUCTION METHOD FASN, SLC27A1, SLC27A2 MAPT 510/4885RAB9A 3276/4885CYP24A1 1784/4885
US-10570269-B2 Composition containing microparticles CHMP4B, EXOSC10, EXOSC9 MAPT 35/4885RAB9A 2989/4885CYP24A1 3200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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