Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 16/20 | 0.47 |
| ▸ | CTSS | P25774 | 16/20 | 0.47 |
| ▸ | CTSV | O60911 | 15/20 | 0.47 |
| ▸ | CTSK | P43235 | 12/20 | 0.47 |
| ▸ | CTSB | P07858 | 9/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906106 | 1.00 | CTSL (0.47) | CTSLCTSSCTSVCTSKCTSB | |
| SCHEMBL1906919 | 0.91 | CTSB (0.40) | CTSLCTSSCTSVCTSKCTSB | |
| SCHEMBL1906321 | 0.91 | KMT2A (0.41) | CTSLCTSSCTSVCTSK | |
| SCHEMBL1908228 | 0.91 | KMT2A (0.41) | CTSLCTSSCTSVCTSK | |
| SCHEMBL1904713 | 0.90 | LCK (0.39) | ITGB1ITGA4 | |
| SCHEMBL1905914 | 0.90 | TACR1 (0.43) | CTSLITGB1ITGA4 | |
| SCHEMBL1905803 | 0.90 | TACR1 (0.43) | CTSLITGB1ITGA4 | |
| SCHEMBL1902249 | 0.89 | MEN1 (0.39) | — | |
| SCHEMBL1905042 | 0.89 | MEN1 (0.39) | — | |
| SCHEMBL1904624 | 0.89 | MEN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051673-A1 | AMINOTHIAZOLE DERIVATIVES USEFUL AS KLK1 INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051673-A1 | AMINOTHIAZOLE DERIVATIVES USEFUL AS KLK1 INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |