⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230060 | 0.82 | — | — | |
| SCHEMBL8121451 | 0.81 | POLB (0.41) | — | |
| SCHEMBL8674 | 0.78 | CA2 (0.46) | — | |
| SCHEMBL27686647 | 0.78 | PIK3CD (0.32) | — | |
| SCHEMBL27822839 | 0.77 | GAA (0.31) | — | |
| SCHEMBL702267 | 0.77 | HPGD (0.39) | — | |
| SCHEMBL16959112 | 0.77 | HDAC4 (0.32) | — | |
| SCHEMBL2956325 | 0.77 | L3MBTL1 (0.38) | — | |
| SCHEMBL27494520 | 0.76 | CA2 (0.43) | — | |
| SCHEMBL28251730 | 0.76 | CA2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 568 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486836-A | Preparation method of 2-aryl-3-carbonyl substituted tetrahydrofuran and tetrahydropyran compound | 遵义医科大学 | 2024-02-02 | — | — | CN | claimed |
| US-11712438-B2 | Phenyl derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-08-01 | — | — | US | claimed |
| CN-116356354-A | Preparation method of 2-aryl-3-sulfonyl substituted tetrahydropyrrole and piperidine compounds | 遵义医科大学 | 2023-06-30 | — | — | CN | claimed |
| CN-116283906-A | Oxindole derivative containing 2-pyridone heterocycle and preparation method and application thereof | 中山大学 | 2023-06-23 | — | — | CN | claimed |
| CN-111620832-B | Multi-substituted oxazoline compound and preparation method thereof | 南京工业大学 | 2022-07-05 | — | — | CN | claimed |
| EP-3997083-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | Idorsia Pharmaceuticals Ltd (CH) | 2022-05-18 | — | — | EP | claimed |
| CN-113105459-B | Triazolopyrimidine derivative and preparation method and application thereof | 五邑大学 | 2022-05-03 | — | — | CN | claimed |
| CN-114127066-A | Inhibitors of indoleamine 2, 3-dioxygenase and/or tryptophan 2, 3-dioxygenase | 爱杜西亚药品有限公司 | 2022-03-01 | — | — | CN | claimed |
| EP-3740493-B1 | INHIBTEURS DE L'INDOLEAMINE 2,3-DIOXYGÉNASE ET/OU DU TRYPTOPHANE DIOXYGÉNASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-12-01 | — | — | EP | claimed |
| CN-113698328-A | Substituted 1, 3-dicarbonyl compound and preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2021-11-26 | — | — | CN | claimed |
| WO-2002024698-A1 | XANTHINE PHOSPHODIESTERASE V INHIBITORS | SCHERING CORPORATION (US) | 2002-03-28 | — | — | WO | claimed |
| CN-1259948-A | 6,7-disubstituted-4-aminopyrido [2,3-D] pyrimidine compounds | ABBOTT LAB (US) | 2000-07-12 | — | — | CN | claimed |
| EP-0979230-A1 | 6,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | Abbott Laboratories (US) | 2000-02-16 | — | — | EP | claimed |
| WO-1998046603-A1 | 6,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 1998-10-22 | — | — | WO | claimed |
| EP-0438209-B1 | Uracil derivatives and pesticides containing the same as active ingredient | NISSAN CHEMICAL IND LTD (JP) | 1994-09-21 | — | — | EP | claimed |
| EP-0219756-B1 | Acrylic amides | SHELL INT RESEARCH (NL) | 1994-01-05 | — | — | EP | claimed |
| US-5116404-A | URACIL DERIVATIVES AND PESTICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-05-26 | — | — | US | claimed |
| EP-0438209-A1 | Uracil derivatives and pesticides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1991-07-24 | — | — | EP | claimed |
| US-4910200-A | Agricultural fungicide | CELAMERCK GMBH & CO. KG (DE) | 1990-03-20 | — | — | US | claimed |
| EP-0219756-A1 | Acrylic amides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-04-29 | — | — | EP | claimed |