Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926417 | 0.85 | PIK3CD (0.32) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL2956325 | 0.84 | L3MBTL1 (0.38) | MAPT | |
| SCHEMBL29180182 | 0.82 | PTPN1 (0.37) | — | |
| SCHEMBL702267 | 0.81 | HPGD (0.39) | MAPT | |
| SCHEMBL190634 | 0.78 | — | — | |
| SCHEMBL4171673 | 0.78 | HPGD (0.37) | EGFRMAPT | |
| SCHEMBL28367075 | 0.78 | TDP1 (0.33) | — | |
| SCHEMBL5685216 | 0.77 | — | — | |
| SCHEMBL21268144 | 0.76 | CYP1A2 (0.41) | EGFRMAPT | |
| SCHEMBL27822844 | 0.76 | ALDH1A1 (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981251-B | Dibenzofuran derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114981251-A | Diphenyl furan derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-1984898-A | Process for production of azulene derivatives and intermediates for the synthesis of the same | ASTELLAS PHARMA INC (JP) | 2007-06-20 | — | — | CN | disclosed |
| CN-1269788-C | Bicyclic aromatic compounds and their use in human or veterinary medicine and in cosmetic processes | GALDERMA RES DEV S N C (FR) | 2006-08-16 | — | — | CN | disclosed |
| CN-1346828-A | Dicyclic aromatic compound and use thereof in human or animal medicine and cosmetic process | CT INTERNAT DE RES ES DERMATOL (FR) | 2002-05-01 | — | — | CN | disclosed |
| CN-1241558-A | Bicyclic aromatic compounds and their use in human or veterinary medicine and in cosmetic processes | GALDERMA RESEARCH DEV S N C (FR) | 2000-01-19 | — | — | CN | disclosed |