Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905621 | 0.88 | TDP2 (0.38) | TDP2EGLN2KDM4EHPGDNPSR1 | |
| SCHEMBL1904874 | 0.76 | TDP2 (0.40) | TDP2EGLN2KDM4EHPGDGRM5 | |
| SCHEMBL1900602 | 0.76 | TDP2 (0.42) | TDP2EGLN2KDM4EHPGDGRM5 | |
| SCHEMBL1900183 | 0.74 | KDM4E (0.35) | TDP2EGLN2KDM4EGRM5LMNA | |
| SCHEMBL1074038 | 0.73 | KDM4E (0.34) | KDM4EHPGDALDH1A1LMNAGAA | |
| SCHEMBL1904366 | 0.70 | ALDH1A1 (0.35) | EGLN2KDM4EHPGDNPSR1RXFP1 | |
| SCHEMBL1075931 | 0.69 | MALT1 (0.36) | ALDH1A1 | |
| SCHEMBL1904865 | 0.68 | EGLN2 (0.34) | EGLN2GRM5ALDH1A1 | |
| SCHEMBL1904943 | 0.65 | OXTR (0.40) | PIK3CA | |
| SCHEMBL1074544 | 0.63 | KDM4E (0.35) | KDM4EHPGDALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056463-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-12 | — | — | WO | claimed |
| WO-2011056463-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |