Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | CPB1 | P15086 | 1/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23849707 | 1.00 | FOLH1 (0.55) | FOLH1CTSLCTSBCTSSCTSK | |
| SCHEMBL29678907 | 0.95 | FOLH1 (0.50) | FOLH1CTSLCTSBCTSSCTSK | |
| SCHEMBL29335184 | 0.92 | CTSB (0.57) | FOLH1CTSLCTSBCTSSCTSK | |
| SCHEMBL4330584 | 0.91 | FOLH1 (0.57) | FOLH1SIRT2SIRT1SIRT3MAPT | |
| SCHEMBL14680407 | 0.91 | CPB1 (0.53) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14680621 | 0.90 | CPB1 (0.46) | FOLH1CTSLCTSBCTSSCTSK | |
| SCHEMBL29679325 | 0.90 | FOLH1 (0.67) | FOLH1CPB1CPB2MEN1KMT2A | |
| SCHEMBL18161563 | 0.90 | FOLH1 (0.67) | FOLH1CPB1CPB2MEN1KMT2A | |
| SCHEMBL29465523 | 0.90 | FOLH1 (0.67) | FOLH1CPB1CPB2MEN1KMT2A | |
| SCHEMBL4330583 | 0.90 | FOLH1 (0.67) | FOLH1CPB1CPB2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025095479-A1 | NOVEL PROSTATE SPECIFIC MEMBRANE ANTIGEN LIGAND AND USE THEREOF | 서울대학교병원 | 2025-05-08 | — | — | WO | disclosed |
| US-10688200-B2 | Urea-based prostate specific membrane antigen (PSMA) inhibitors for imaging and therapy | FIVE ELEVEN PHARMA INC. (US) | 2020-06-23 | — | — | US | disclosed |
| US-20170189568-A1 | UREA-BASED PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS FOR IMAGING AND THERAPY | FIVE ELEVEN PHARMA INC. | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189568-A1 | UREA-BASED PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS FOR IMAGING AND THERAPY | KLK3, FOLH1, UTS2R | FOLH1 2/4885CTSL 930/4885CTSB 1877/4885 |
| US-10688200-B2 | Urea-based prostate specific membrane antigen (PSMA) inhibitors for imaging and therapy | KLK3, FOLH1, UTS2R | FOLH1 2/4885CTSL 930/4885CTSB 1877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.