Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | CPB1 | P15086 | 1/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19065207 | 1.00 | FOLH1 (0.55) | FOLH1CTSLCTSBCTSSCTSK | |
| SCHEMBL29678907 | 0.95 | FOLH1 (0.50) | FOLH1CTSLCTSBCTSSCTSK | |
| SCHEMBL29335184 | 0.92 | CTSB (0.57) | FOLH1CTSLCTSBCTSSCTSK | |
| SCHEMBL4330584 | 0.91 | FOLH1 (0.57) | FOLH1SIRT2SIRT1SIRT3MAPT | |
| SCHEMBL14680407 | 0.91 | CPB1 (0.53) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14680621 | 0.90 | CPB1 (0.46) | FOLH1CTSLCTSBCTSSCTSK | |
| SCHEMBL29679325 | 0.90 | FOLH1 (0.67) | FOLH1CPB1CPB2MEN1KMT2A | |
| SCHEMBL18161563 | 0.90 | FOLH1 (0.67) | FOLH1CPB1CPB2MEN1KMT2A | |
| SCHEMBL29465523 | 0.90 | FOLH1 (0.67) | FOLH1CPB1CPB2MEN1KMT2A | |
| SCHEMBL4330583 | 0.90 | FOLH1 (0.67) | FOLH1CPB1CPB2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397968-B1 | UREA-BASED PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS FOR IMAGING AND THERAPY | FIVE ELEVEN PHARMA INC (US) | 2021-09-29 | — | — | EP | disclosed |