Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 11/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24368187 | 0.97 | OPRD1 (0.57) | OPRD1OPRM1OPRK1CTDSP1 | |
| Diacetylmorphine SCHEMBL11424713 | 0.82 | OPRD1 (0.76) | OPRD1OPRM1OPRK1 | |
| SCHEMBL16126173 | 0.82 | MRGPRX2 (0.62) | OPRD1OPRM1OPRK1 | |
| SCHEMBL19485064 | 0.82 | MRGPRX2 (0.62) | OPRD1OPRM1OPRK1 | |
| SCHEMBL25575471 | 0.82 | MRGPRX2 (0.62) | OPRD1OPRM1OPRK1 | |
| SCHEMBL14107504 | 0.82 | OPRM1 (0.66) | OPRD1OPRM1OPRK1CTDSP1 | |
| Diacetylmorphine SCHEMBL13998950 | 0.81 | OPRD1 (0.81) | OPRD1OPRM1OPRK1 | |
| Diacetylmorphine SCHEMBL16922130 | 0.81 | OPRD1 (0.81) | OPRD1OPRM1OPRK1 | |
| Diacetylmorphine SCHEMBL16922136 | 0.81 | OPRD1 (0.81) | OPRD1OPRM1OPRK1 | |
| Diacetylmorphine SCHEMBL16183153 | 0.81 | OPRD1 (0.81) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9694069-B2 | 6-acetylmorphine analogs, and methods for their synthesis and use | ALERE SAN DIEGO, INC. (US) | 2017-07-04 | — | — | US | disclosed |