Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25575471 | 1.00 | MRGPRX2 (0.62) | MRGPRX2MAPTOPRD1OPRM1OPRK1 | |
| SCHEMBL19485064 | 1.00 | MRGPRX2 (0.62) | MRGPRX2MAPTOPRD1OPRM1OPRK1 | |
| SCHEMBL13575270 | 0.84 | OPRD1 (0.56) | MRGPRX2MAPTOPRD1OPRM1OPRK1 | |
| SCHEMBL12091202 | 0.82 | MRGPRX2 (0.78) | MRGPRX2MAPTOPRD1OPRM1OPRK1 | |
| SCHEMBL14153816 | 0.82 | MRGPRX2 (0.78) | MRGPRX2MAPTOPRD1OPRM1OPRK1 | |
| SCHEMBL14107502 | 0.82 | MRGPRX2 (0.78) | MRGPRX2MAPTOPRD1OPRM1OPRK1 | |
| SCHEMBL19068338 | 0.82 | OPRD1 (0.58) | OPRD1OPRM1OPRK1 | |
| Diacetylmorphine SCHEMBL7206795 | 0.82 | OPRD1 (0.80) | MRGPRX2OPRD1OPRM1OPRK1 | |
| SCHEMBL19484989 | 0.81 | OPRD1 (0.47) | MRGPRX2MAPTOPRD1OPRM1OPRK1 | |
| SCHEMBL24368187 | 0.81 | OPRD1 (0.57) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3470416-B1 | 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | ALERE SAN DIEGO INC (US) | 2022-04-27 | — | — | EP | disclosed |
| EP-3470416-A1 | 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | Alere San Diego, Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| US-20170296654-A1 | 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | ALERE SAN DIEGO, INC. | 2017-10-19 | — | — | US | disclosed |
| US-9694069-B2 | 6-acetylmorphine analogs, and methods for their synthesis and use | ALERE SAN DIEGO, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-9694069-B2 | 6-acetylmorphine analogs, and methods for their synthesis and use | ALERE SAN DIEGO, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20160022809-A1 | 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | ALERE SAN DIEGO, INC. | 2016-01-28 | — | — | US | disclosed |
| US-20160022809-A1 | 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | ALERE SAN DIEGO, INC. | 2016-01-28 | — | — | US | disclosed |
| WO-2014152657-A1 | 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | ALERE SAN DIEGO, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022809-A1 | 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | DNPEP, CRHBP, AANAT | MRGPRX2 347/4885MAPT 1767/4885OPRD1 30/4885 |
| US-20170296654-A1 | 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE | DNPEP, CRHBP, AANAT | MRGPRX2 347/4885MAPT 1767/4885OPRD1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.