Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17960860 | 0.84 | ADORA3 (0.54) | RXFP1ADORA3ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8947213 | 0.83 | LMNA (0.49) | ADORA3GAARAB9ASMN1; SMN2MAPT | |
| SCHEMBL3647705 | 0.83 | SMN1; SMN2 (0.56) | ADORA3KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL3650394 | 0.82 | ADORA3 (0.59) | RXFP1ADORA3ALDH1A1KDM4ERAB9A | |
| SCHEMBL27651786 | 0.82 | MCL1 (0.47) | RXFP1SMN1; SMN2MAPTL3MBTL1LMNA | |
| SCHEMBL4114732 | 0.80 | ALDH1A1 (0.51) | RXFP1ADORA3ALDH1A1KDM4EGAA | |
| SCHEMBL3649882 | 0.75 | AURKA (0.51) | ADORA3FAAH | |
| SCHEMBL12112411 | 0.74 | ADORA3 (0.44) | RXFP1ADORA3ALDH1A1KDM4ERAB9A | |
| SCHEMBL9108540 | 0.72 | HSD17B1 (0.46) | ADORA3ALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL3649527 | 0.72 | NR4A2 (0.56) | MEN1KMT2ALMNAMCL1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190698-A1 | ENZYME INTERACTING AGENTS | CENTRAL ADELAIDE LOCAL HEALTH NETWORK INCORPORATED (AU) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190698-A1 | ENZYME INTERACTING AGENTS | SMPD1, SMPD2, ASAH1 | RXFP1 4688/4885ADORA3 3829/4885ALDH1A1 1318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.