SCHEMBL19080178

SCHEMBL19080178

c1ccc2cc3c(cc2c1)oc1cc2cc(-c4ccc(-c5c6ccccc6c(-c6ccc7sc8ccccc8c7c6)c6ccccc56)cc4)ccc2cc13

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.34
CYP1A2 P05177 1/20 0.32
ESR1 P03372 3/20 0.32
ESR2 Q92731 3/20 0.32
PTPN1 P18031 3/20 0.32
S1PR4 O95977 3/20 0.31
S1PR5 Q9H228 3/20 0.31
PTPN7 P35236 1/20 0.31
DUSP3 P51452 1/20 0.31
PTPN12 Q05209 1/20 0.31
PTPN22 Q9Y2R2 1/20 0.31
PGR P06401 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PIM3 Q86V86 1/20 0.30
CASP3 P42574 1/20 0.30
SENP7 Q9BQF6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19076925 0.95 GPR3 (0.33) GPR3CYP1A2PTPN1PTPN7DUSP3
SCHEMBL19076603 0.94 AHR (0.34) GPR3CYP1A2PTPN1ALDH1A1MAPT
SCHEMBL19080177 0.92 ABCG2 (0.33) GPR3CYP1A2PGRRAB9A
SCHEMBL19076871 0.92 ESR1 (0.34) GPR3CYP1A2ESR1ESR2PTPN1
SCHEMBL19081959 0.92 ESR1 (0.34) CYP1A2ESR1ESR2S1PR4S1PR5
SCHEMBL19080179 0.91 CYP1A1 (0.38) CYP1A2ESR2ALDH1A1MAPTHPGD
SCHEMBL24342845 0.91 AHR (0.33) CYP1A2ESR1ESR2S1PR4S1PR5
SCHEMBL19110061 0.91 CASP3 (0.33) GPR3CYP1A2ESR1ESR2S1PR4
SCHEMBL22253762 0.90 GPR3 (0.36) GPR3CYP1A2ESR1ESR2PTPN7
SCHEMBL17246867 0.90 GPR3 (0.38) GPR3CYP1A2ESR1ESR2PTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194571-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194571-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170194571-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNA1 GPR3 3219/4885CYP1A2 621/4885ESR1 153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.