SCHEMBL19081522

SCHEMBL19081522

c1ccc(-c2c3ccccc3c(-c3cccc(-c4ccc5c(c4)oc4c5ccc5c6cc7ccccc7cc6oc54)c3)c3ccccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.40
ESR2 Q92731 6/20 0.40
ALOX5 P09917 2/20 0.35
DYRK1A Q13627 1/20 0.35
HSD17B1 P14061 2/20 0.34
HSD17B2 P37059 2/20 0.34
PLA2G2A P14555 2/20 0.34
PLA2G4A P47712 2/20 0.34
ERAP1 Q9NZ08 1/20 0.34
PLA2G10 O15496 1/20 0.34
CYP1A2 P05177 4/20 0.33
CYP2C9 P11712 3/20 0.33
CYP2C19 P33261 3/20 0.33
CYP1A1 P04798 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2B6 P20813 2/20 0.33
PRKDC P78527 2/20 0.33
CYP1B1 Q16678 2/20 0.33
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19081509 0.93 PLA2G2A (0.41) ESR1ESR2ALOX5PLA2G2APLA2G4A
SCHEMBL16067726 0.93 ESR1 (0.43) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL19076327 0.91 ALOX5 (0.39) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL16067821 0.90 ESR1 (0.40) ESR1ESR2HSD17B1HSD17B2PLA2G2A
SCHEMBL17932007 0.90 ESR1 (0.45) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL19081553 0.90 ALOX5 (0.38) ESR1ESR2ALOX5CYP1A2CYP2C19
SCHEMBL19079938 0.90 CYP1A1 (0.40) ESR1ESR2HSD17B1HSD17B2PLA2G2A
SCHEMBL19081422 0.89 ESR1 (0.42) ESR1ESR2PLA2G2APLA2G4AERAP1
SCHEMBL17944117 0.89 ALOX5 (0.44) ALOX5DYRK1APLA2G2APLA2G4AERAP1
SCHEMBL16067682 0.89 ESR1 (0.46) ESR1ESR2ALOX5CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-04 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNT1 ESR1 225/4885ESR2 542/4885ALOX5 1939/4885
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 ESR1 225/4885ESR2 542/4885ALOX5 1939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.