SCHEMBL190823

SCHEMBL190823

C=Cc1ccc2cc(O[Si](C(C)C)(C(C)C)C(C)C)ccc2c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.34
NQO2 P16083 3/20 0.33
ALDH1A1 P00352 2/20 0.32
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CHRNB4 P30926 2/20 0.31
CHRNA3 P32297 2/20 0.31
CHRNA7 P36544 2/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP2C19 P33261 1/20 0.31
PTGS1 P23219 1/20 0.31
RELA Q04206 1/20 0.31
EGFR P00533 1/20 0.31
PDGFRB P09619 1/20 0.31
PDGFRA P16234 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3791568 0.84 ALDH1A1 (0.44) TRPA1ALDH1A1TDP1CHRNB4CHRNA3
SCHEMBL190591 0.83 ALDH1A3 (0.44) ALDH1A1TDP1MAPTALDH1A3TTR
SCHEMBL13347421 0.83 ALDH1A1 (0.39) TRPA1NQO2ALDH1A1TP53TDP1
SCHEMBL5888734 0.81 TP53 (0.44) TRPA1NQO2ALDH1A1TP53TDP1
SCHEMBL31670075 0.77 CYP2A6 (0.52) TDP1HTR2CCYP1A2ALOX5
SCHEMBL15298750 0.75 CYP1A2 (0.50) ALDH1A1TDP1CYP1A2
SCHEMBL29566387 0.74 CYP1A2 (0.54) TRPA1NQO2ALDH1A1TP53CYP3A4
SCHEMBL29566047 0.74 CYP1A2 (0.54) TRPA1NQO2ALDH1A1TP53CYP3A4
SCHEMBL190030 0.74 CYP1A2 (0.54) TRPA1NQO2ALDH1A1TP53CYP3A4
SCHEMBL6584082 0.74 MTNR1A (0.38) NQO2ALDH1A1MAPTCYP2C9HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9896587-B2 Planarizing agents and devices NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-02-20 US disclosed
US-9896587-B2 Planarizing agents and devices NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-02-20 US disclosed
US-9896587-B2 Planarizing agents and devices NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-02-20 US disclosed
US-20140299858-A1 PLANARIZING AGENTS AND DEVICES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-10-09 US disclosed
US-20140299858-A1 PLANARIZING AGENTS AND DEVICES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-10-09 US disclosed
US-20140299858-A1 PLANARIZING AGENTS AND DEVICES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-10-09 US disclosed
US-8709291-B2 Planarizing agents and devices PLEXTRONICS, INC. (US) 2014-04-29 US disclosed
US-8709291-B2 Planarizing agents and devices PLEXTRONICS, INC. (US) 2014-04-29 US disclosed
US-8709291-B2 Planarizing agents and devices PLEXTRONICS, INC. (US) 2014-04-29 US disclosed
US-20120277367-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. 2012-11-01 US disclosed
US-20120277367-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. 2012-11-01 US disclosed
US-8187501-B2 Planarizing agents and devices PLEXTRONICS, INC. (US) 2012-05-29 US disclosed
US-8187501-B2 Planarizing agents and devices PLEXTRONICS, INC. (US) 2012-05-29 US disclosed
EP-2250207-B1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS INC (US) 2012-01-04 EP disclosed
EP-2250207-A1 PLANARIZING AGENTS AND DEVICES Plextronics, Inc. (US) 2010-11-17 EP disclosed
US-20100072462-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. 2010-03-25 US disclosed
US-20100072462-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. 2010-03-25 US disclosed
WO-2009111339-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. (US) 2009-09-11 WO disclosed