SCHEMBL190591

SCHEMBL190591

CC(C)[Si](Oc1ccc2cc(C=O)ccc2c1)(C(C)C)C(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 1/20 0.44
CYP2A6 P11509 7/20 0.40
ALDH1A1 P00352 6/20 0.40
TSHR P16473 1/20 0.37
TYR P14679 1/20 0.36
RAB9A P51151 1/20 0.36
KDM4E B2RXH2 2/20 0.34
DRD1 P21728 1/20 0.34
AOX1 Q06278 1/20 0.34
TRIM24 O15164 1/20 0.34
HPGD P15428 1/20 0.34
ALDH5A1 P51649 1/20 0.34
ABAT P80404 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TRIM33 Q9UPN9 1/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PTGER4 P35408 1/20 0.33
TTR P02766 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3697133 0.84 ALDH1A3 (0.57) ALDH1A3CYP2A6ALDH1A1TYRKDM4E
SCHEMBL190823 0.83 TRPA1 (0.34) ALDH1A3ALDH1A1TDP1TTRMAPT
SCHEMBL13347426 0.83 ALDH1A3 (0.52) ALDH1A3CYP2A6ALDH1A1TYRRAB9A
SCHEMBL13347377 0.83 ALDH1A3 (0.52) ALDH1A3CYP2A6ALDH1A1TYRRAB9A
SCHEMBL13347423 0.81 RELA (0.44) ALDH1A3RAB9ATDP1
SCHEMBL25221171 0.81 SRC (0.47) ALDH1A3ALDH1A1RAB9ADRD1HPGD
SCHEMBL30533425 0.81 SRC (0.47) ALDH1A3ALDH1A1RAB9ADRD1HPGD
SCHEMBL31670075 0.77 CYP2A6 (0.52) CYP2A6RAB9AKDM4ETDP1
SCHEMBL1161803 0.75 CA12 (0.56) ALDH1A3CYP2A6ALDH1A1TSHRRAB9A
SCHEMBL15298750 0.75 CYP1A2 (0.50) CYP2A6ALDH1A1KDM4EHPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9896587-B2 Planarizing agents and devices NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-02-20 US disclosed
US-9896587-B2 Planarizing agents and devices NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-02-20 US disclosed
US-9896587-B2 Planarizing agents and devices NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-02-20 US disclosed
US-20140299858-A1 PLANARIZING AGENTS AND DEVICES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-10-09 US disclosed
US-20140299858-A1 PLANARIZING AGENTS AND DEVICES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-10-09 US disclosed
US-20140299858-A1 PLANARIZING AGENTS AND DEVICES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-10-09 US disclosed
US-8709291-B2 Planarizing agents and devices PLEXTRONICS, INC. (US) 2014-04-29 US disclosed
US-8709291-B2 Planarizing agents and devices PLEXTRONICS, INC. (US) 2014-04-29 US disclosed
US-8709291-B2 Planarizing agents and devices PLEXTRONICS, INC. (US) 2014-04-29 US disclosed
US-20120277367-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. 2012-11-01 US disclosed
US-20120277367-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. 2012-11-01 US disclosed
US-8187501-B2 Planarizing agents and devices PLEXTRONICS, INC. (US) 2012-05-29 US disclosed
US-8187501-B2 Planarizing agents and devices PLEXTRONICS, INC. (US) 2012-05-29 US disclosed
EP-2250207-B1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS INC (US) 2012-01-04 EP disclosed
EP-2250207-A1 PLANARIZING AGENTS AND DEVICES Plextronics, Inc. (US) 2010-11-17 EP disclosed
US-20100072462-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. 2010-03-25 US disclosed
US-20100072462-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. 2010-03-25 US disclosed
WO-2009111339-A1 PLANARIZING AGENTS AND DEVICES PLEXTRONICS, INC. (US) 2009-09-11 WO disclosed