Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 7/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19082604 | 1.00 | KDM4E (0.50) | KDM4EPSMD14NR4A2CREBBPLMNA | |
| SCHEMBL19082608 | 0.94 | KDM4E (0.46) | KDM4EPSMD14NR4A2CREBBPLMNA | |
| SCHEMBL30151495 | 0.88 | TSHR (0.52) | KDM4EPSMD14NR4A2CREBBPLMNA | |
| SCHEMBL1538693 | 0.83 | ALDH1A1 (0.53) | KDM4EPSMD14NR4A2LMNATSHR | |
| SCHEMBL19258188 | 0.83 | NR4A2 (0.55) | KDM4EPSMD14NR4A2CREBBPLMNA | |
| SCHEMBL70429 | 0.83 | LMNA (0.59) | KDM4EPSMD14NR4A2CREBBPLMNA | |
| SCHEMBL29434198 | 0.83 | BRD4 (0.59) | KDM4ENR4A2CREBBPLMNATSHR | |
| SCHEMBL70381 | 0.83 | BRD4 (0.59) | KDM4ENR4A2CREBBPLMNATSHR | |
| SCHEMBL8765365 | 0.82 | KDM4E (0.45) | KDM4EPSMD14NR4A2CREBBPLMNA | |
| SCHEMBL7651251 | 0.81 | CA1 (0.48) | KDM4ENR4A2CREBBPLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9885863-B2 | Dye compounds for an electrowetting element | AMAZON TECHNOLOGIES, INC. (US) | 2018-02-06 | — | — | US | disclosed |
| US-20170192222-A1 | DYE COMPOUNDS FOR AN ELECTROWETTING ELEMENT | AMAZON TECHNOLOGIES, INC. | 2017-07-06 | — | — | US | disclosed |