SCHEMBL8765365

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19082607	0.82	KDM4E (0.50)	KDM4EPSMD14NR4A2CREBBPLMNA
	SCHEMBL19082604	0.82	KDM4E (0.50)	KDM4EPSMD14NR4A2CREBBPLMNA
	SCHEMBL30151495	0.82	TSHR (0.52)	KDM4EPSMD14NR4A2CREBBPLMNA
	SCHEMBL5378153	0.80	ALDH1A1 (0.56)	KDM4ETSHRALDH1A1BRD4MEN1
	SCHEMBL5375991	0.78	TYMS (0.51)	KDM4EPSMD14NR4A2ALDH1A1HSD17B10
	SCHEMBL19258188	0.77	NR4A2 (0.55)	KDM4EPSMD14NR4A2CREBBPLMNA
	SCHEMBL19082608	0.77	KDM4E (0.46)	KDM4EPSMD14NR4A2CREBBPLMNA
	SCHEMBL70381	0.77	BRD4 (0.59)	KDM4ENR4A2CREBBPLMNATSHR
	SCHEMBL29434198	0.77	BRD4 (0.59)	KDM4ENR4A2CREBBPLMNATSHR
	SCHEMBL70429	0.77	LMNA (0.59)	KDM4EPSMD14NR4A2CREBBPLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.