Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 4/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.33 |
| ▸ | PAK4 | O96013 | 3/20 | 0.33 |
| ▸ | RET | P07949 | 3/20 | 0.33 |
| ▸ | LTK | P29376 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.33 |
| ▸ | CLK2 | P49760 | 3/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.33 |
| ▸ | JAK3 | P52333 | 3/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.33 |
| ▸ | MST1R | Q04912 | 3/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19082955 | 0.86 | PRKCI (0.33) | NUDT1JAK2DAPK3PAK4RET | |
| SCHEMBL19082959 | 0.80 | LMNA (0.36) | NUDT1CLK2PTK2LRRK2AURKB | |
| SCHEMBL19082952 | 0.78 | JAK2 (0.32) | NUDT1JAK2DAPK3PAK4RET | |
| SCHEMBL19082948 | 0.78 | PRKCI (0.36) | NUDT1JAK2DAPK3PAK4RET | |
| SCHEMBL29829901 | 0.78 | PIK3CA (0.34) | AURKAMAPK1CHEK1 | |
| SCHEMBL17017328 | 0.78 | PIK3CA (0.34) | AURKAMAPK1CHEK1 | |
| SCHEMBL19082953 | 0.77 | NUDT1 (0.34) | NUDT1JAK2DAPK3PAK4RET | |
| SCHEMBL19082949 | 0.72 | KDR (0.34) | JAK2DAPK3PAK4RETLTK | |
| SCHEMBL19082946 | 0.71 | ADORA2A (0.40) | JAK2JAK3ADORA2AADORA1MAPK1 | |
| SCHEMBL19082969 | 0.69 | CLK2 (0.40) | NUDT1CLK2PTK2AURKBCLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190704-A1 | COMPOSITIONS AND METHODS USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | Mitokinin, LLC (US) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190704-A1 | COMPOSITIONS AND METHODS USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | NLN, HAGH, MT-ND2 | NUDT1 447/4885JAK2 4247/4885DAPK3 1575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.