Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15199103 | 1.00 | POLB (0.46) | POLBCYP2D6CYP2C19EPHX1PSMB5 | |
| SCHEMBL16727369 | 1.00 | POLB (0.46) | POLBCYP2D6CYP2C19EPHX1PSMB5 | |
| SCHEMBL12425624 | 0.92 | CYP2D6 (0.50) | CYP2D6CYP2C19EPHX1PSMB5ALDH1A1 | |
| SCHEMBL23729169 | 0.87 | ALDH1A1 (0.45) | POLBCYP2D6CYP2C19EPHX1PSMB5 | |
| SCHEMBL26763896 | 0.84 | SMN1; SMN2 (0.55) | POLBCYP2D6CYP2C19EPHX1PSMB5 | |
| SCHEMBL1768109 | 0.84 | EPHX1 (0.50) | CYP2D6CYP2C19EPHX1PSMB5ALDH1A1 | |
| SCHEMBL17787637 | 0.83 | EPHX1 (0.42) | CYP2D6CYP2C19EPHX1PSMB5ALDH1A1 | |
| SCHEMBL10270129 | 0.83 | ROCK2 (0.46) | CYP2D6CYP2C19EPHX1PSMB5ALDH1A1 | |
| SCHEMBL26716801 | 0.83 | MMP8 (0.51) | CYP2D6CYP2C19EPHX1PSMB5ALDH1A1 | |
| SCHEMBL24474359 | 0.83 | ROCK2 (0.46) | CYP2D6CYP2C19EPHX1PSMB5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017117275-A1 | SILICA NANOPARTICLE WITH PLATINUM ANTI-CANCER AGENT | CITY OF HOPE (US) | 2017-07-06 | — | — | WO | disclosed |