Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10270129 | 1.00 | ROCK2 (0.46) | ROCK2ROCK1LMNATDP1EPHX1 | |
| SCHEMBL12425624 | 0.90 | CYP2D6 (0.50) | EPHX1CYP2D6CYP2C19PSMB5ALDH1A1 | |
| SCHEMBL24474316 | 0.89 | ALDH1A1 (0.43) | ROCK2ROCK1LMNATDP1EPHX1 | |
| SCHEMBL15199103 | 0.83 | POLB (0.46) | EPHX1CYP2D6CYP2C19PSMB5ALDH1A1 | |
| SCHEMBL17132547 | 0.83 | LMNA (0.49) | ROCK2ROCK1LMNATDP1CYP2D6 | |
| SCHEMBL16727369 | 0.83 | POLB (0.46) | EPHX1CYP2D6CYP2C19PSMB5ALDH1A1 | |
| SCHEMBL19083853 | 0.83 | POLB (0.46) | EPHX1CYP2D6CYP2C19PSMB5ALDH1A1 | |
| SCHEMBL24202435 | 0.83 | MTNR1A (0.43) | ROCK2ROCK1LMNATDP1PSMB5 | |
| SCHEMBL1768109 | 0.82 | EPHX1 (0.50) | EPHX1CYP2D6CYP2C19PSMB5ALDH1A1 | |
| SCHEMBL26763896 | 0.82 | SMN1; SMN2 (0.55) | EPHX1CYP2D6CYP2C19PSMB5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696959-B2 | Nanoparticle-cell construct with platinum anti-cancer agent | CITY OF HOPE (US) | 2023-07-11 | — | — | US | disclosed |
| WO-2022111521-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州多域生物技术有限公司 | 2022-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696959-B2 | Nanoparticle-cell construct with platinum anti-cancer agent | CD47, TP53, CD63 | ROCK2 2310/4885ROCK1 1926/4885LMNA 2866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.