SCHEMBL19084202

SCHEMBL19084202

O=C1C=CC(O)N1c1ccc(CO)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
VHL P40337 1/20 0.39
ELOC Q15369 1/20 0.39
ELOB Q15370 1/20 0.39
MGLL Q99685 4/20 0.35
FAAH O00519 2/20 0.35
CHKA P35790 1/20 0.35
TYR P14679 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA12 O43570 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
TSHR P16473 1/20 0.30
P2RX3 P56373 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19003835 0.87 CA1 (0.40) MGLLFAAHCA1CA2
SCHEMBL19054156 0.81 MGLL (0.64) MGLLFAAH
SCHEMBL23094941 0.79 MGLL (0.56) MGLLFAAH
SCHEMBL19291106 0.78 MGLL (0.43) MGLLFAAHCA1CA2
SCHEMBL10067910 0.78 MGLL (0.43) MGLLFAAHCA1CA2
SCHEMBL2662733 0.77 GSK3A (0.46) MGLLFAAH
SCHEMBL19084203 0.76 DDAH1 (0.53) CA1CA2CA12CA9TSHR
SCHEMBL23616010 0.75 KMT2A (0.49) CA1CA2TSHRP2RX3
SCHEMBL25113055 0.74 MGLL (0.39) MGLLFAAH
SCHEMBL24595426 0.72 CYP3A4 (0.37) CA1CA2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9834627-B2 Polymers derived from norbornadiene and maleic anhydride and use thereof PROMERUS, LLC (US) 2017-12-05 US disclosed
US-20170190810-A1 POLYMERS DERIVED FROM NORBORNADIENE AND MALEIC ANHYDRIDE AND USE THEREOF PROMERUS, LLC (US) 2017-07-06 US disclosed