Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | STAT6 | P42226 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698304 | 0.91 | TP53 (0.77) | ALDH1A1MAPK1TP53HSD17B10CYP1A2 | |
| SCHEMBL21291914 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPK1TP53HSD17B10CYP1A2 | |
| SCHEMBL17443143 | 0.78 | MAPK1 (0.44) | ALDH1A1MAPK1TP53HSD17B10CYP1A2 | |
| SCHEMBL11835122 | 0.78 | GPR35 (0.60) | ALDH1A1MAPK1TP53HSD17B10CYP1A2 | |
| SCHEMBL8738471 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MAPK1TP53HSD17B10CYP1A2 | |
| SCHEMBL70180 | 0.75 | GPR35 (0.58) | ALDH1A1MAPK1TP53HSD17B10CYP1A2 | |
| SCHEMBL7027831 | 0.73 | GPR35 (0.50) | ALDH1A1MAPK1TP53HSD17B10CYP1A2 | |
| SCHEMBL5707256 | 0.73 | ALDH1A1 (0.59) | ALDH1A1MAPK1HSD17B10HSP90AA1GPR35 | |
| SCHEMBL227018 | 0.73 | GPR35 (0.56) | ALDH1A1MAPK1TP53HSD17B10CYP1A2 | |
| SCHEMBL16974397 | 0.73 | GPR35 (0.56) | ALDH1A1MAPK1TP53HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190842-A1 | O-HYDROXY-FUNCTIONALIZED DIAMINES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190842-A1 | O-HYDROXY-FUNCTIONALIZED DIAMINES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE | ALKBH3, AOC1, PAM | ALDH1A1 540/4885MAPK1 3644/4885TP53 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.