Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | CCKAR | P32238 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18672972 | 0.85 | HTR2B (0.41) | HTR2BSLC6A2SLC6A3DRD2ADRA2C | |
| SCHEMBL16804117 | 0.85 | HTR2B (0.41) | HTR2BSLC6A2SLC6A3DRD2ADRA2C | |
| SCHEMBL18673148 | 0.82 | DRD2 (0.49) | HTR2BSLC6A2SLC6A3DRD2ADRA2C | |
| SCHEMBL16804119 | 0.82 | DRD2 (0.49) | HTR2BSLC6A2SLC6A3DRD2ADRA2C | |
| SCHEMBL12654910 | 0.68 | HTR2B (0.45) | HTR2BSLC6A2SLC6A3DRD2ADRA2C | |
| SCHEMBL18673181 | 0.66 | DRD2 (0.69) | HTR2BSLC6A2SLC6A3DRD2ADRA2C | |
| SCHEMBL18673156 | 0.66 | ALDH1A1 (0.44) | HTR2BSLC6A2SLC6A3DRD2ADRA2C | |
| SCHEMBL18673134 | 0.61 | — | — | |
| SCHEMBL12908690 | 0.59 | DRD2 (0.43) | HTR2BSLC6A2SLC6A3DRD2ADRA2C | |
| SCHEMBL12942984 | 0.59 | DRD2 (0.43) | HTR2BSLC6A2SLC6A3DRD2ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170192025-A1 | METHODS OF MONITORING ADHERENCE TO LURASIDONE THERAPY | AMERITOX LLC (US) | 2017-07-06 | — | — | US | disclosed |