Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16804116 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2TSHRPOLBLDHA | |
| SCHEMBL19084395 | 0.81 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2TSHRPOLBLDHA | |
| SCHEMBL19084426 | 0.79 | HTR2B (0.55) | ALDH1A1SMN1; SMN2TSHRPOLBLDHA | |
| SCHEMBL18673181 | 0.77 | DRD2 (0.69) | HTR2BDRD2ADRA2CHTR2AABCB11 | |
| SCHEMBL18673134 | 0.68 | — | — | |
| SCHEMBL19084396 | 0.66 | HTR2B (0.34) | ALDH1A1POLBHTR2BDRD2ADRA2C | |
| SCHEMBL10469851 | 0.64 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2TSHRPOLBSORD | |
| SCHEMBL16229130 | 0.63 | DRD2 (0.62) | ALDH1A1SMN1; SMN2HTR2BDRD2ADRA2C | |
| SCHEMBL12445891 | 0.63 | DRD2 (0.62) | ALDH1A1SMN1; SMN2HTR2BDRD2ADRA2C | |
| SCHEMBL27596185 | 0.63 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2TSHRPOLBLDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9606132-B2 | Methods of monitoring adherence to lurasidone therapy | AMERITOX, LTD. (US) | 2017-03-28 | — | — | US | disclosed |