SCHEMBL19085049

SCHEMBL19085049

CCOC(=O)c1ccccc1-c1ccc2oc3cc(Br)c4ccccc4c3c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.46
KDM4E B2RXH2 2/20 0.45
GAA P10253 2/20 0.45
ALDH1A1 P00352 1/20 0.45
GLA P06280 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.43
CCNB2 O95067 1/20 0.43
CDK1 P06493 1/20 0.43
CCNB1 P14635 1/20 0.43
CCNA2 P20248 1/20 0.43
CCNE1 P24864 1/20 0.43
CDK2 P24941 1/20 0.43
CCNB3 Q8WWL7 1/20 0.43
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
PRNP P04156 1/20 0.42
TNKS O95271 1/20 0.42
PLA2G1B P04054 1/20 0.41
ATG4B Q9Y4P1 1/20 0.41
GABRP O00591 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19085046 0.92 MEN1 (0.44) ALOX5KDM4EGAAALDH1A1GLA
SCHEMBL19077664 0.85 HSP90AA1 (0.40) KDM4ECCNB2CDK1CCNB1CCNB3
SCHEMBL19084992 0.79 ALOX5 (0.48) ALOX5KDM4EGAAALDH1A1GLA
SCHEMBL19110412 0.76 GABRP (0.46) ALOX5KDM4EGAAALDH1A1GLA
SCHEMBL19077627 0.76 CHEK1 (0.39) KDM4EMEN1KMT2ATSHRRAB9A
SCHEMBL22228561 0.76 WEE1 (0.40) ALOX5KDM4EALDH1A1CDK1CCNB1
SCHEMBL13966911 0.74 TSHR (0.53) ALOX5KDM4EALDH1A1MEN1KMT2A
SCHEMBL19077661 0.73 HSP90AA1 (0.35) ALOX5ALDH1A1CDK1CCNB1CCNE1
SCHEMBL19085016 0.73 TSHR (0.41) ALOX5KDM4EGAAALDH1A1L3MBTL1
SCHEMBL28454296 0.72 TSHR (0.57) ALOX5KDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194573-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170194573-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 ALOX5 1939/4885KDM4E 3720/4885GAA 3736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.