Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8861632 | 0.80 | MGAM (0.47) | MGAMACHENOS3NOS1NOS2 | |
| SCHEMBL7171268 | 0.80 | TP53 (0.42) | CYP1A2CYP2A6TP53NOTUMIDO1 | |
| SCHEMBL7162484 | 0.80 | TRPA1 (0.42) | MGAMALDH1A1MAPTACHETRPA1 | |
| SCHEMBL1908526 | 0.80 | PNMT (0.48) | MGAMALDH1A1SMN1; SMN2ACHENOS3 | |
| SCHEMBL25714425 | 0.78 | TP53 (0.52) | CYP1A2CYP2A6TP53NOTUMIDO1 | |
| Bromide SCHEMBL8345607 | 0.78 | MGAM (0.39) | MGAMACHE | |
| SCHEMBL4572715 | 0.77 | ACHE (0.48) | MGAMMAPTL3MBTL1ACHE | |
| SCHEMBL166894 | 0.77 | TP53 (0.61) | CYP1A2CYP2A6TP53NOTUMIDO1 | |
| SCHEMBL7160970 | 0.77 | TAAR1 (0.57) | CYP1A2CYP2A6LMNASMN1; SMN2ACHE | |
| SCHEMBL3106769 | 0.77 | TP53 (0.39) | CYP1A2CYP2A6TP53NOTUMIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093406-B2 | Cyclic sulfones with aminobenzyl substitution useful as BACE inhibitors | NOVARTIS AG (CH) | 2012-01-10 | — | — | US | disclosed |
| EP-1250365-A2 | TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS | Basell Polypropylen GmbH (DE) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001048034-A2 | TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-07-05 | — | — | WO | disclosed |
| EP-0352150-A1 | Process for the preparation of meta-substituted fluoro or alkyl benzene derivatives | RHONE-POULENC CHIMIE (FR) | 1990-01-24 | — | — | EP | disclosed |
| EP-0349373-A2 | Process for the preparation of ortho-substituted fluoro or alkyl benzene derivatives | RHONE-POULENC CHIMIE (FR) | 1990-01-03 | — | — | EP | disclosed |