Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 6/20 | 0.58 |
| ▸ | GRIA3 | P42263 | 6/20 | 0.58 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.55 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.49 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | GRM6 | O15303 | 3/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.49 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.49 |
| ▸ | GRM8 | O00222 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (R,S)-Ampa SCHEMBL23242452 | 1.00 | GRIA1 (0.58) | GRIA1GRIA3GRIA2GRIA4GRIK1 | |
| (R,S)-Ampa SCHEMBL68799 | 0.90 | GRIA1 (0.69) | GRIA1GRIA3GRIA2GRIA4GRIK1 | |
| (R,S)-Ampa SCHEMBL2458874 | 0.90 | GRIA1 (0.69) | GRIA1GRIA3GRIA2GRIA4GRIK1 | |
| (S)-Ampa SCHEMBL667915 | 0.90 | GRIA1 (0.69) | GRIA1GRIA3GRIA2GRIA4GRIK1 | |
| (R,S)-Ampa SCHEMBL7200262 | 0.89 | GRIA1 (0.68) | GRIA1GRIA3GRIA2GRIA4GRIK1 | |
| (R,S)-Ampa SCHEMBL7200264 | 0.89 | GRIA1 (0.68) | GRIA1GRIA3GRIA2GRIA4GRIK1 | |
| (R,S)-Ampa SCHEMBL6553747 | 0.87 | GRIA1 (0.56) | GRIA1GRIA3GRIA2GRIA4GRIK1 | |
| SCHEMBL3731488 | 0.81 | GRIA1 (0.54) | GRIA1GRIA3GRIA2GRIA4GRIK1 | |
| SCHEMBL12506417 | 0.81 | GRIA1 (0.54) | GRIA1GRIA3GRIA2GRIA4GRIK1 | |
| (S)-Ampa SCHEMBL28091565 | 0.80 | GRIA1 (0.53) | GRIA1GRIA3GRIA2GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3190181-B1 | CORNEAL ENDOTHELIAL CELL MARKER | UNIV OSAKA (JP) | 2020-06-17 | — | — | EP | disclosed |
| US-20170253855-A1 | CORNEAL ENDOTHELIAL CELL MARKER | OSAKA UNIVERSITY (JP) | 2017-09-07 | — | — | US | disclosed |
| EP-3190181-A1 | CORNEAL ENDOTHELIAL CELL MARKER | Osaka University (JP) | 2017-07-12 | — | — | EP | disclosed |