Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 5/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.39 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (R,S)-Ampa SCHEMBL2458874 | 0.85 | GRIA1 (0.69) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (S)-Ampa SCHEMBL667915 | 0.85 | GRIA1 (0.69) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL68799 | 0.85 | GRIA1 (0.69) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL7200262 | 0.84 | GRIA1 (0.68) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL7200264 | 0.84 | GRIA1 (0.68) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL23242452 | 0.80 | GRIA1 (0.58) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL19086372 | 0.80 | GRIA1 (0.58) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| (R,S)-Ampa SCHEMBL6553747 | 0.78 | GRIA1 (0.56) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| SCHEMBL28471680 | 0.77 | GRIA1 (0.47) | GRIA1GRIA3GRIA2GRIA4MAPT | |
| SCHEMBL24115240 | 0.74 | GRIA1 (0.37) | GRIA1GRIA3GRIA2GRIA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105873570-A | Sustained release depot formulations of therapeutic proteins and uses thereof | 奇尼塔有限责任公司 | 2016-08-17 | — | — | CN | disclosed |