Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537851 | 0.76 | CYP1A2 (0.42) | HTTGAALMNAALDH1A1 | |
| SCHEMBL17469426 | 0.72 | CYP3A4 (0.31) | ALDH1A1HPGDIDH1 | |
| SCHEMBL23385556 | 0.72 | CYP3A4 (0.31) | ALDH1A1HPGDIDH1 | |
| SCHEMBL8305504 | 0.68 | FPR2 (0.44) | ALDH1A1 | |
| SCHEMBL6696454 | 0.68 | GAA (0.48) | GAAALDH1A1 | |
| SCHEMBL23666760 | 0.68 | L3MBTL1 (0.47) | HTTGAA | |
| SCHEMBL8186836 | 0.67 | KDM4E (0.56) | LMNA | |
| SCHEMBL8185859 | 0.67 | GOT1 (0.33) | — | |
| SCHEMBL8191779 | 0.67 | HPGDS (0.38) | ALDH1A1 | |
| SCHEMBL2074934 | 0.67 | HSD17B10 (0.44) | HTTGAALMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999338-B1 | KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-12 | — | — | EP | disclosed |