Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.61 |
| ▸ | HTR2A | P28223 | 2/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | DRD5 | P21918 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.61 |
| ▸ | HTR1D | P28221 | 1/20 | 0.61 |
| ▸ | HTR1B | P28222 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | HTR1E | P28566 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | GPR183 | P32249 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20470107 | 0.85 | DRD2 (0.64) | HTR1ADRD2HTR2A | |
| SCHEMBL19549049 | 0.85 | DRD2 (0.62) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL30124153 | 0.85 | DRD2 (0.62) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL21783311 | 0.83 | HTR1A (0.60) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL19549056 | 0.82 | HTR1A (0.59) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL12437737 | 0.82 | DRD2 (0.64) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL28981516 | 0.81 | HTR1A (0.59) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL16449729 | 0.81 | DRD2 (0.66) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL19888525 | 0.80 | DRD2 (0.67) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL19563749 | 0.80 | DRD2 (0.64) | HTR1ADRD2HTR2AADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017115287-A1 | PROCESS FOR THE PREPARATION OF QUINOLINE-2(1H)-ONE DERIVATIVES | HONOUR (R&D) (IN) | 2017-07-06 | — | — | WO | disclosed |