Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | DRD5 | P21918 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | HTR1D | P28221 | 1/20 | 0.60 |
| ▸ | HTR1B | P28222 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | HTR1E | P28566 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | GPR183 | P32249 | 1/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19549056 | 0.89 | HTR1A (0.59) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL28981516 | 0.88 | HTR1A (0.59) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL30124153 | 0.84 | DRD2 (0.62) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL19549049 | 0.84 | DRD2 (0.62) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL19088099 | 0.83 | HTR1A (0.61) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL4302011 | 0.81 | HTR1A (0.65) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL4302769 | 0.81 | HTR1A (0.65) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL19888525 | 0.79 | DRD2 (0.67) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL19563749 | 0.78 | DRD2 (0.64) | HTR1ADRD2HTR2AADRB2ADRB1 | |
| SCHEMBL1037444 | 0.78 | DRD2 (0.64) | HTR1ADRD2HTR2AADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11123300-B2 | Immediate release tablet of a benzothiophene compound | HEXAL AG (DE) | 2021-09-21 | — | — | US | disclosed |
| US-20200069593-A1 | Immediate Release Tablet of a Benzothiophene Compound | HEXAL AG (DE) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069593-A1 | Immediate Release Tablet of a Benzothiophene Compound | SLC18A1, BRIX1, SLC6A4 | HTR1A 14/4885DRD2 878/4885HTR2A 37/4885 |
| US-11123300-B2 | Immediate release tablet of a benzothiophene compound | SLC18A1, BRIX1, SLC6A4 | HTR1A 14/4885DRD2 878/4885HTR2A 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.