Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19066214 | 0.83 | CHRM3 (0.48) | PTPN2PTPN1PTPN6GPR119KDM4E | |
| SCHEMBL19088797 | 0.83 | PTPN2 (0.47) | PTPN2PTPN1PTPN6ALDH1A1GPR119 | |
| SCHEMBL828713 | 0.82 | CHRM3 (0.51) | PTPN2PTPN1PTPN6ALDH1A1GPR119 | |
| SCHEMBL19088791 | 0.80 | CHRM3 (0.45) | GPR119KMT2A | |
| SCHEMBL4983940 | 0.80 | GPR119 (0.48) | PTPN2PTPN1PTPN6GPR119NPC1 | |
| SCHEMBL19088802 | 0.79 | HPGDS (0.46) | PTPN2PTPN1PTPN6GPR119 | |
| SCHEMBL19088794 | 0.79 | STS (0.47) | PTPN2PTPN1PTPN6GPR119MAPT | |
| SCHEMBL19066183 | 0.79 | CHRM3 (0.50) | PTPN2PTPN1PTPN6GPR119KDM4E | |
| SCHEMBL19066187 | 0.78 | GPR119 (0.43) | PTPN2PTPN1PTPN6ALDH1A1GPR119 | |
| SCHEMBL829401 | 0.78 | GPR119 (0.50) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849035-B | Phenyl heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-107849035-A | Phenyl heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2018-03-27 | — | — | CN | disclosed |
| WO-2017114377-A1 | BENZYL HETEROCYCLIC COMPOUND DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2017-07-06 | — | — | WO | disclosed |