Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228062 | 0.87 | HPGDS (0.45) | GPR119HPGDSPTPN2PTPN1PTPN6 | |
| SCHEMBL3171133 | 0.87 | PTPN2 (0.58) | GPR119MKNK1PTPN2PTPN1PTPN6 | |
| SCHEMBL828713 | 0.86 | CHRM3 (0.51) | GPR119PTPN2PTPN1PTPN6MEN1 | |
| SCHEMBL4014959 | 0.84 | CHRM3 (0.47) | KMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL6106121 | 0.83 | GPR119 (0.62) | GPR119MKNK1HDAC1HDAC2MEN1 | |
| SCHEMBL2773558 | 0.80 | GPR119 (0.58) | GPR119HPGDSMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19088803 | 0.80 | PTPN2 (0.46) | GPR119PTPN2PTPN1PTPN6KMT2A | |
| SCHEMBL23648774 | 0.79 | HDAC2 (0.50) | GPR119MKNK1PTPN2PTPN1PTPN6 | |
| SCHEMBL16692867 | 0.79 | KCNQ4 (0.47) | GPR119MKNK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19088802 | 0.78 | HPGDS (0.46) | GPR119HPGDSPTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090873-A1 | Sulfonamide derivatives | PFIZER INC. | 2008-04-17 | — | — | US | disclosed |
| US-20080090873-A1 | Sulfonamide derivatives | PFIZER INC. | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090873-A1 | Sulfonamide derivatives | SULT2A1, SULT1A1, STS | GPR119 3829/4885MKNK1 3485/4885HPGDS 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.