Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23759873 | 0.92 | L3MBTL3 (0.37) | L3MBTL3L3MBTL1PIM1ALDH1A1KDM1A | |
| SCHEMBL26818871 | 0.84 | HRH3 (0.36) | L3MBTL3L3MBTL1MBTD1KDM1ATP53 | |
| SCHEMBL8259610 | 0.83 | HRH3 (0.39) | L3MBTL3L3MBTL1PIM1MBTD1ALDH1A1 | |
| SCHEMBL26022672 | 0.83 | L3MBTL3 (0.46) | L3MBTL3L3MBTL1MBTD1ALDH1A1KDM4E | |
| SCHEMBL19119393 | 0.83 | L3MBTL3 (0.46) | L3MBTL3L3MBTL1MBTD1ALDH1A1KDM4E | |
| SCHEMBL24541593 | 0.83 | CHRM2 (0.33) | ALDH1A1KDM4ETP53 | |
| SCHEMBL24996266 | 0.82 | — | — | |
| SCHEMBL22456338 | 0.82 | HRH3 (0.38) | L3MBTL3L3MBTL1PIM1MBTD1 | |
| SCHEMBL24060987 | 0.80 | L3MBTL3 (0.37) | L3MBTL3L3MBTL1PIM1MBTD1ALDH1A1 | |
| SCHEMBL21361601 | 0.79 | SIGMAR1 (0.41) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640248-A1 | AMINOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Beijing Adamadle Biotechnology Limited Liability Company (CN) | 2020-04-22 | — | — | EP | disclosed |
| WO-2017114500-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | 恩瑞生物医药科技（上海）有限公司 | 2017-07-06 | — | — | WO | disclosed |